A little north of Serpent Mound is Fort Hill State Memorial, where an uphill hike rewards visitors with one of the best preserved Hopewell-era hilltop enclosures in North America. The scenic farmland nearby is home to many Amish families, often seen in their distinctive horse-drawn buggies. Beyond Bainbridge, the Paint Creek Valley was lined in antiquity with a magnificent array of geometric earthworks. The most extensive now are the Seip Earthworks and Seip-Preiser Mound, just east of town. Atop the steep, prominent hill just opposite Bourneville lies Spruce Hill Fort, a stone-walled hilltop enclosure even larger than Fort Ancient.

Remains of the Hopewell Mound Group, after which archaeologists named the whole culture because of its vast complexity and astonishing artifacts, is reachable along the North Fork of Paint Creek, just before entering Chillicothe. Remains of the large 3-lobed mound stand in an open field, while extensive walls, ditches, and ponds survive intact along the far hilltop.